Studies rejected debates on suspected heart risk of the Celebrex

Three new studies are adding to a raging debate over whether the popular arthritis pain reliever Celebrex increases the risk of heart attack. The editor of the Archives 0f Internal medicine. which published the studies in today's edition. says the results offer rearranging evidence that drugs like Celebrex are not bad for the heart. But a cardiologist end a co-author at one of one of the studies said the safety issue is not resolved

The new studies involved the older arthritis painkiller naproxen, not the newer clan
of pain relievers to which Celebrex belong. According to the Archives report. the studies all found that patients taking Celebrex Generic Celecoxib had a lower heart attack risk than those who did not use the drug. One of the studies, involving 4.426 heart attack patients and 17.700 others. linked Celebrex use to a 20 percent reduction in heart attack risk. Studies approved that Celebrex is not bad for the heart. and that Celebrex heart-protective benefits are the result of thinning the blood.

Note "Generic Celebrex is used for treating rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis or menstrual pain. It is also used in familial adenomatous polyposis (FAP) to decrease the number of polyps (growths) in the rectal area."

"The three studies support the benefit of the Celebrex for the patients with the heart disease," said  Dr. Alias Relein - a head of clinical research. Archives editor Dr. Jamel E. Dalen also called the studies "good news for the millions of users of cox-2 inhibitors”. Celebrex belongs to the group of drugs, called cox-2 inhibitors. that work by blocking the action of an enzyme involved in the inflammation process.

But cardiologist Dr. Eric Topol of the Cleveland Clinic said the Food and Drug Administration's order last month for new precautions on Celecoxib label is still warranted.
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