How Adalimumab Is Revolutionizing Treatment for Chronic Inflammatory Conditions

Posted by MrMed Pharmacy
6
Sep 8, 2024
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Inflammation is like your body’s rescue team. When there's a threat, such as an infection, injury, or irritant, your immune system acts swiftly to manage the situation. Acute inflammation, such as redness, heat, swelling, and pain, is your body’s way of healing and protecting itself. This response is usually short-lived and resolves once the problem is addressed. While acute inflammation is generally beneficial, it can become problematic when it persists longer than usual or occurs inappropriately. 

What is chronic inflammation?

Chronic inflammation is prolonged and can remain for months or even years. It often results from the body’s inability to eliminate the initial cause of inflammation completely or from a persistent low-level irritant. It can be triggered by several factors, such as

  • Infections: Some infections, like those caused by some bacteria or viruses, may stay in the body, leading to chronic inflammation.

  • Environmental factors: Long-term exposure to pollutants, chemicals, or allergens can lead to chronic inflammation.

  • Lifestyle Factors: Poor diet, obesity, and less physical activity are known risk factors for chronic inflammation.

What are the symptoms of chronic inflammation?

Chronic inflammation symptoms can be less obvious than those of acute inflammation, which includes:

  • Fatigue

  • Joint stiffness or pain

  • Pain in abdomen

  • Mouth sores 

  • Skin rashes

  • Chest discomfort

  • Anxiety and depression

  • More prone to catching infections

  • Gastrointestinal disturbances

How does chronic inflammation affect your health?

When inflammation goes wrong, the effects it has on your health can be wide-ranging, such as 

  1. Cardiovascular Health: Chronic inflammation can lead to artery damage and lead to heart disease.

  2. Metabolic Health: It plays a vital role in type 2 diabetes by impairing the body's ability to manage blood sugar.

  3. Mental Health: Studies suggest that chronic inflammation may influence mood disorders and cognitive function, linking it to depression and anxiety.

Can inflammation cause an autoimmune response?

Autoimmune disorders develop when the immune system mistakenly attacks its own tissues. This self-driven inflammation can cause significant damage. Conditions involving this type of dysfunction include:

  • Rheumatoid arthritis

  • Lupus

  • Multiple sclerosis 

What is the treatment for chronic inflammation?

But when inflammation becomes chronic, you need to control it to prevent damage to healthy tissues. It is very crucial to know the cause in order to administer a tailored treatment. Some of the treatment options to combat inflammation and treat chronic inflammatory diseases include:

  • Supplements: Some supplements — like vitamins, zinc, resveratrol, and omega-3 — may reduce inflammation and enhance repair. Always talk to your doctor before taking any new supplements.

  • Nonsteroidal anti-inflammatory drugs (NSAIDs): These over-the-counter (OTC) medicines reduce inflammation. Your doctor may recommend ibuprofen, aspirin or naproxen. Don’t take NSAIDs for more than ten days continuously without talking to your doctor.

  • Corticosteroid: Your doctor may give you an injection to decrease inflammation at a specific joint or muscle. Be sure to follow your doctor’s instructions on how to take your medication.

What is the medicine adalimumab used for?

Adalimumab is a biological medicine that has potentially changed the treatment of chronic inflammatory conditions. It is an antirheumatic agent that belongs to the TNF (tumour necrosis factor) inhibitors. It is given intravenously under the skin, which helps the medicine work directly where it is needed, targeting inflammation more accurately.

What are the uses of adalimumab injection?

The Adalimumab injection uses is to treat conditions such as

  • Hidradenitis suppurativa

  • Ulcerative colitis

  • Ankylosing spondylitis

  • Crohn’s disease

  • Enthesitis-related arthritis

  • Non-infectious uveitis

  • Plaque psoriasis

  • Polyarticular juvenile idiopathic arthritis

  • Rheumatoid arthritis

  • Psoriatic arthritis

What are the side effects of Adalimumab injection?

Some of the side effects caused by adalimumab injection include

  • Headache and fever

  • Rash or severe skin reactions

  • Upper respiratory infections

  • Sinusitis

  • Injection site reactions

  • Bone problems and infections

  • Severe respiratory problems

  • Liver injury

  • GI bleeding

  • Abnormal blood count values

  • Heart problems or abnormal heartbeat

What are the best anti-inflammatory foods?

Adopting a diet that is rich in anti-inflammatory properties may support overall health and reduce chronic inflammation. Having nutrient-dense foods that have been shown to reduce inflammation helps manage symptoms and support long-term health. Food that is rich in anti-inflammatory properties are

  • Fatty Fish: Rich in omega-3 fatty acids, which have anti-inflammatory effects. 

  • Berries: Packed with antioxidants and phytochemicals that can reduce inflammation. 

  • Leafy Greens: Such as kale, spinach, and Swiss chard, contain vitamins and antioxidants that help combat inflammation.

  • Nuts: Provide healthy fats and antioxidants that can lower inflammation. 

  • Turmeric: It contains curcumin, a compound with strong anti-inflammatory effects.

  • Ginger: It has compounds that can help reduce inflammation and pain.

  • Tomatoes: Rich in lycopene and antioxidants that help reduce inflammation.

  • Extra virgin Olive Oil: It has oleocanthal, which has anti-inflammatory properties.

  • Green Tea: Packed with polyphenols, particularly epigallocatechin gallate, which has anti-inflammatory properties.

Wrapping up

Adalimumab is making new waves in the treatment of chronic inflammatory conditions by targeting inflammation with precision and efficacy. This revolutionary medication offers a most promising option for patients with chronic inflammation. It enhances quality of life and helps manage symptoms more effectively. By adopting a diet rich in anti-inflammatory properties and proper medication, chronic inflammation can be managed with ease.

“Even in the darkest moments of battling disease, hope and resilience pave the way to healing and recovery”.

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