What are the risks and complications associated with kidney transplant?

Posted by Dr Priya Sharma
4
May 10, 2023
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Kidney transplant is a major surgical procedure that can provide significant benefits for people with end-stage kidney disease. However, like all surgeries, there are risks and potential complications associated with kidney transplant. Some of the common risks and complications associated with kidney transplant include: Rejection: The most common complication of kidney transplant is rejection, which occurs when the recipient's immune system recognizes the transplanted kidney as a foreign object and attacks it. Rejection can occur at any time after the transplant and may require additional treatment, including immunosuppressive medications. Infection: Transplant recipients are at increased risk of developing infections due to the immunosuppressive medications they take to prevent rejection. These infections can be serious and may require hospitalization. Bleeding: The surgery to transplant the kidney can cause bleeding, and in some cases, additional surgery may be necessary to control the bleeding. Blood clots: Transplant recipients are at increased risk of developing blood clots, which can lead to serious complications such as stroke or heart attack. Cardiovascular disease: Kidney transplant recipients are at increased risk of developing cardiovascular disease, which can include heart attack and stroke. Cancer: Immunosuppressive medications used to prevent rejection can increase the risk of developing certain types of cancer, such as skin cancer and lymphoma. Diabetes: Transplant recipients may develop diabetes due to the immunosuppressive medications and other factors. It is important to note that not all transplant recipients will experience these complications, and many complications can be successfully treated with prompt medical attention. The benefits of kidney transplant often outweigh the risks, but it is important to discuss the risks and potential complications with your healthcare team before undergoing the procedure. What are the infections associated with kidney transplant? Kidney transplant recipients are at increased risk of developing infections due to the immunosuppressive medications they take to prevent rejection. Some of the infections that are commonly associated with kidney transplant include: Urinary tract infections (UTIs): UTIs are one of the most common infections in kidney transplant recipients. They can occur at any time after the transplant and can be caused by bacteria that enter the bladder or urinary tract. Cytomegalovirus (CMV): CMV is a common virus that can cause serious illness in kidney transplant recipients. It can affect various organs and may cause symptoms such as fever, fatigue, and enlarged lymph nodes. Herpes simplex virus (HSV): HSV is a virus that can cause cold sores and genital herpes. In kidney transplant recipients, HSV can cause serious illness and may require antiviral medications to treat. Varicella-zoster virus (VZV): VZV is the virus that causes chickenpox and shingles. Kidney transplant recipients who have not had chickenpox or the vaccine are at risk of developing a severe form of the disease. Fungal infections: Fungal infections can occur in kidney transplant recipients, particularly in those who have received high doses of immunosuppressive medications. Fungal infections can be difficult to treat and may require long-term antifungal medications. Tuberculosis (TB): TB is a bacterial infection that can affect the lungs and other organs. Kidney transplant recipients are at increased risk of developing TB, especially if they have received immunosuppressive medications. It is important for kidney transplant recipients to take precautions to prevent infections, such as practicing good hygiene and avoiding contact with sick people. If an infection does occur, prompt medical attention is necessary to prevent serious complications. How does Diabetes affect the success of my kidney transplant? Diabetes can affect the success of kidney transplant in several ways. Diabetes is a chronic condition that affects how the body processes sugar and can lead to kidney damage, known as diabetic nephropathy. If you have diabetes and are undergoing a kidney transplant, here are some ways it can affect the success of the transplant: Increased risk of complications: Diabetes can increase the risk of complications during and after the kidney transplant, including infection, bleeding, and cardiovascular problems. Risk of kidney damage: If you have diabetes, you may be at increased risk of developing kidney damage after the transplant, which can reduce the lifespan of the transplanted kidney. Risk of rejection: Diabetes can affect the immune system, which can increase the risk of rejection of the transplanted kidney. Need for insulin: After the transplant, it may be necessary to adjust your insulin regimen, as immunosuppressive medications used to prevent rejection can affect blood sugar levels.
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