Peptic ulcer and 12 duodenal ulcer

General description

Peptic ulcer of the stomach and duodenal ulcer is a chronic, seasonal recurrent disease of the stomach and duodenum, manifested by a defect in the mucous membrane (ulcers). These disorders occur against the background of destabilization of the nervous and humoral mechanisms in the human body, which regulate secretory-reparative processes in the stomach and duodenum. Peptic ulcer disease is characterized by periods of exacerbation (spring and autumn) and remission. Ulcer healing results in scar formation.

The prevalence of the disease in all countries is about 4-6% of the adult population. With a full-fledged medical screening of patients, this percentage increases to 20-25%.

The peak incidence occurs at the age of 30-45 years. Mainly in men aged 35-50 years, gastric ulcer and duodenal ulcer occurs 3-4 times more often.

Causes of occurrence

• The presence of Helicobacter pylori in the stomach and duodenum, which is the main etiological factor in the occurrence of ulcers. The influence of other bacteria has not been proven
• Violation of the diet
• Alcohol and tobacco abuse
• Long-term use of drugs that affect the gastric mucosa, the main ones: NSAIDs and glucocorticosteroids (prednisolone)
• Emotional stress, stress
• Genetic predisposition
• Metabolic disorders
• Hypoavitaminosis

Symptoms of the disease

• Aching or cramping pains, weak in the epigastric region, more often occur on an empty stomach or immediately after eating
• Constant heartburn, especially at night and morning hours, sour belching
• Nausea
• Belching of air, sour or bitter taste
• Severity in the epigastric region after a meal, a feeling of fast stomach filling
• Decreased appetite
• When bleeding from ulcers, vomit of "coffee grounds" appears, dark stools (melena)
• With perforation of ulcers - severe, dagger pain in the epigastric region, nausea, vomiting, painful tension of the abdominal muscles

Diagnostics

• General clinical analysis of blood, urine
• Stool analysis for coprogram
• Fecal occult blood test
• Biochemical blood test (liver function tests, cholesterol, alkaline phosphatase)
• ECG
• X-ray of the chest organs in 2 projections and X-ray of the abdominal organs (to exclude perforation of ulcers)
• X-ray of the esophagus, stomach with barium mixture
• Ultrasound of the hepatobiliary system
• Daily pH monitoring in the lower esophagus and stomach
• EGDS
• Non-invasive tests for the determination of Helicobacter pylori. (Respiratory)

Treatment

The main treatment for chronic gastritis consists of adhering to a healthy lifestyle and proper balanced nutrition or you can buy buy aciphex.

Components of a healthy lifestyle and proper balanced nutrition:

• Refusal to use alcoholic, strongly carbonated drinks
• Weight loss with obesity
• To give up smoking
• Avoiding large meals and late hours

If these non-drug treatments do not bring relief, drugs are used.