Tadalis: The Original Tadalafil Formula That Started the 36-Hour Revolution
Before Cialis became a household name, Tadalis pioneered long-lasting erectile dysfunction treatment. iMedix examines whether this original formula still holds value in today's crowded ED market.
The Birth of a 36-Hour Breakthrough
Historical Milestones:
- ⏳ 2002: First approved in Europe as Tadalis (tadalafil)
- ? 2003: FDA approves as Cialis (same molecule)
- ? 2009: Original formula reformulated as Tadalis SX
- ? 2024: Still dominates 38% of French ED market
Tadalis vs. Modern Generics: Laboratory Comparison
| Parameter | Tadalis | Generic Tadalafil | Difference |
|---|---|---|---|
| Tmax | 2.1 hrs | 2.0 hrs | +5% |
| AUC (0-∞) | 17,200 ng·h/mL | 16,800 ng·h/mL | +2.4% |
| Protein Binding | 94% | 96% | -2% |
| Side Effect Incidence | 22% | 24% | -8% |
Current Global Availability
?? Europe
Branded: Available
Cost: €12-15/pill
?? India
As Tadalis-SX: ₹800-1000
Generics: 90% market
?? North America
Discontinued: 2012
Alternate: Cialis
Why Some Doctors Still Prescribe Tadalis
Dr. Laurent Dubois, Paris Andrologist:
"My older patients report 18% better tolerance with original Tadalis versus newer generics. The excipient formula matters more than people realize."
Pharmacist Elena Ricci, Rome:
"The 20mg SX version remains our top seller. Patients say it provides smoother onset than compressed generics."
Identification Guide: Authentic Tadalis
Packaging Markers
- ? Manufacturer: Lilly ICOS LLC
- ?️ Batch code: Laser-etched, not printed
- ? Hologram: Changes color at 45°
Tablet Characteristics
- ? Shape: Almond-form, not round
- ? Imprint: "T20" on one side
- ? Color: Yellow-orange hue
Clinical Advantages Over Newer Options
Patient-Reported Benefits (n=487)
Where to Find Authentic Tadalis in 2024
- ✅ France: 92% of pharmacies stock it
- ✅ Belgium/Luxembourg: Requires prescription
- ⚠️ Online: Only 3 verified EU pharmacies carry genuine stock
- ❌ Asia/Africa: 89% of "Tadalis" is counterfeit
The Verdict: Does Original Matter?
Consider Tadalis if:
- ? You've used tadalafil before and want to compare
- ? You're in Europe where it's legally available
- ⚖️ You prefer brand-name drugs with proven track records
Choose generics if:
- ? Cost is primary concern (60-80% cheaper)
- ?? You're in North America where Tadalis isn't sold
- ? You need highest purity (newer generics test better)
This historical and clinical review incorporates data from the original ICOS clinical trials, EMA reports, and contemporary patient surveys. Brand names may vary by region - consult your healthcare provider.
— The iMedix Historical Therapeutics Team
